You're exhausted. Bone-deep, can't-get-out-of-bed exhausted. But you can't relax. Your mind races. Your heart pounds. You feel wired and anxious despite being completely depleted.
This doesn't make sense. How can you be exhausted AND wired at the same time?
The answer is cortisol resistance.
It's the same mechanism as insulin resistance, but instead of your cells ignoring insulin, they're ignoring cortisol. Your body keeps producing cortisol (or trying to), but your cells have stopped responding to it.
This is what creates the "wired and tired" state that destroys people. And it's why Stage 3 adrenal dysfunction is so brutal to recover from.
Every cell in your body has cortisol receptors. When cortisol binds to these receptors, it triggers specific responses: mobilize glucose, suppress inflammation, regulate your nervous system, control your sleep-wake cycle.
When cortisol signaling works properly, you feel alert when you need to be, relaxed ...
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